Investigating Orthobiologics After Platelet-Rich Plasma and Photobiomodulation Treatment of Knee Osteoarthritis

This study will investigate the effect of photobiomodulation treatment (PBMT) on synovial and serum inflammatory and progenitor cells using precision medicine techniques pre- and post- treatment of knee osteoarthritis across four treatment groups: 1) standard physical therapy, or physical therapy combined with 2) PRP 3) PBMT or 4) PRP and PBMT.